2-Hydrazinoethanol → HCID 20279739, compound

HRID 1247867Notes

Reaction equation

HRID 1247867 reaction equation
[OH:1][CH2:2][CH2:3][NH:4][NH2:5].[CH2:6]([N:10]=[C:11]=[O:12])[CH2:7][CH2:8][CH3:9]>O1CCCC1>[CH2:6]([NH:10][C:11]([N:4]([CH2:3][CH2:2][OH:1])[NH2:5])=[O:12])[CH2:7][CH2:8][CH3:9]

Participants

4

Reactant 2

HCID 80172-HydrazinoethanolHCID 8110Butyl isocyanate

Product 1

HCID 20279739HCID 20279739, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent2×

Procedure

To 7.61 g (0.1 moles) 2-hydroxyethylhydrazine in 150 mL tetrahydrofuran was added dropwise over a period of about 1/2 hour with stirring 9.91 g (0.1 mole) butylisocyanate in 50 mL tetrahydro-furan. At the end of the addition period stirring was continued until the solution cooled to room temperature. A small amount of precipitate was removed by filtration, and the solvent was evaporated to yield a viscous pale oil, N-butyl-1-(2-hydroxyethyl)hydrazinecarboxamide quantitatively. This structure was confirmed by NMR analysis.

Workup

  1. additionAt the end of the addition period
  2. customA small amount of precipitate was removed by filtration
  3. customthe solvent was evaporated

Sources & evidence

ORD record
ord-0f372ee6d32c488b829fe8c30c64b343
Source dataset
uspto-grants-1985_06
Patent number
US04521325

Reaction notes

Loading…