2-Hydrazinoethanol → N-Cyclohexyl-1-(2-Hydroxyethyl)Hydrazinecarboxamide

HRID 1247868Notes

Reaction equation

HRID 1247868 reaction equation
[OH:1][CH2:2][CH2:3][NH:4][NH2:5].[CH:6]1([N:12]=[C:13]=[O:14])[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1>O1CCCC1>[CH:6]1([NH:12][C:13]([N:4]([CH2:3][CH2:2][OH:1])[NH2:5])=[O:14])[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1

Participants

4

Reactant 2

HCID 80172-HydrazinoethanolHCID 18502Cyclohexyl isocyanate

Product 1

HCID 20279738N-Cyclohexyl-1-(2-Hydroxyethyl)Hydrazinecarboxamide

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent2×

Procedure

To a solution of 2-hydroxyethylhydrazine (7.15 g, 0.09 moles) in 125 mL tetrahydrofuran was added dropwise with stirring 11.76 g (0.09 moles) cyclohexyl isocyanate in 70 mL tetrahydrofuran. The solution was stirred overnight at room temperature, and the solvent was evaporated to yield quantitatively a pale viscous oil which slowly crystallizes.

Workup

  1. customthe solvent was evaporated
  2. customto yield quantitatively a pale viscous oil which
  3. customslowly crystallizes

Sources & evidence

ORD record
ord-41be6d99dc374605bb5724d8b3e81156
Source dataset
uspto-grants-1985_06
Patent number
US04521325

Reaction notes

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