3-Aminopyridine → HCID 23713652, compound

HRID 1247923Notes

Reaction equation

HRID 1247923 reaction equation
[NH2:1][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][CH:7]=1.O.O[CH2:10][S:11]([O-:14])(=[O:13])=[O:12].[Na+:15]>O>[N:4]1[CH:5]=[CH:6][CH:7]=[C:2]([NH:1][CH2:10][S:11]([O-:14])(=[O:13])=[O:12])[CH:3]=1.[Na+:15]

Participants

4

Reactant 2

HCID 100093-AminopyridineHCID 23713651HCID 23713651, compound

Product 1

HCID 23713652HCID 23713652, compoundYield 58.9%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
80 °C

Procedure

A mixture of 3-aminopyridine (2.82 g) and sodium hydroxymethanesulfonate monohydrate (9.12 g) in water (40 ml) was stirred for 1.5 hours at 80° C. The solution was concentrated to yield a precipitate and stood for several hours. The resulting precipitate was filtered, washed with ethanol and dried to give sodium 3-pyridylaminomethanesulfonate (3.71 g), mp 211° to 220° C.

Workup

  1. concentrationThe solution was concentrated
  2. customto yield a precipitate
  3. waitstood for several hours
  4. filtrationThe resulting precipitate was filtered
  5. washwashed with ethanol
  6. customdried

Sources & evidence

ORD record
ord-281ec7f184334710b9b26d2008fc192a
Source dataset
uspto-grants-1985_06
Patent number
US04521413

Reaction notes

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