3-Acetylpyridine → HCID 54355643, compound

HRID 1247955Notes

Reaction equation

HRID 1247955 reaction equation
[C:1]([C:4]1[CH:5]=[N:6][CH:7]=[CH:8][CH:9]=1)(=[O:3])[CH3:2].CO[CH:12](OC)[N:13]([CH3:15])[CH3:14]>C1C=CC=CC=1>[CH2:12]([N:13]([CH2:15][CH2:7][CH2:8][CH3:9])[CH:14]=[CH:2][C:1]([C:4]1[CH:5]=[N:6][CH:7]=[CH:8][CH:9]=1)=[O:3])[CH2:2][CH2:1][CH3:4]

Participants

4

Reactant 2

HCID 95893-AcetylpyridineHCID 78373Dimethylformamide dimethyl acetal

Product 1

HCID 54355643HCID 54355643, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

A mixture of 0.10 mole of 3-acetylpyridine and 0.10 mole of N,N-dimethylformamide dimethylacetal in 100 ml of benzene was refluxed for 12 hours. The solvent was removed, giving 3-dibutylamino-1-(3-pyridinyl)-2-propen-1-one.

Workup

  1. temperaturewas refluxed for 12 hours
  2. customThe solvent was removed

Sources & evidence

ORD record
ord-67d2d75d53514a2a9a5e829fec826ab3
Source dataset
uspto-grants-1985_06
Patent number
US04521422

Reaction notes

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