Sodium Chloride → HCID 20278419, compound

HRID 1248085Notes

Reaction equation

HRID 1248085 reaction equation
[C:1]([CH:4]([C:9](=[O:32])[CH:10]([O:12][C:13]1[CH:18]=[CH:17][C:16]([O:19][C:20]2[CH:29]=[N:28][C:27]3[C:22](=[CH:23][C:24]([Cl:31])=[C:25]([Cl:30])[CH:26]=3)[N:21]=2)=[CH:15][CH:14]=1)[CH3:11])C(OC)=O)(=[O:3])[CH3:2].ClC1C=C2C(=CC=1Cl)N=C(OC1C=CC(OC(C)C(Cl)=O)=CC=1)C=N2.[Na].COC(=O)CC(C)=O.[Cl-].[Na+]>CS(C)=O>[Cl:30][C:25]1[CH:26]=[C:27]2[C:22](=[CH:23][C:24]=1[Cl:31])[N:21]=[C:20]([O:19][C:16]1[CH:15]=[CH:14][C:13]([O:12][CH:10]([CH3:11])[C:9](=[O:32])[CH2:4][C:1](=[O:3])[CH3:2])=[CH:18][CH:17]=1)[CH:29]=[N:28]2

Participants

7

Reactant 5

HCID 5234Sodium ChlorideHCID 7757Methyl acetoacetateHCID 5360545SodiumHCID 20278420HCID 20278420, compoundHCID 541011542-[4-(6,7-Dichloro-2-quinoxalinyloxy)phenoxy]propionic acid chloride

Product 1

HCID 20278419HCID 20278419, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

Again, following the same procedures, methyl 2-acetyl-4-[4-(6,7-dichloro-2-quinoxalinyloxy)phenoxy]-3-oxopentanoate (XIV; X' is chloro and X" is chloro) is prepared from 2-[4-(6,7-dichloro-2-quinoxalinyloxy)phenoxy]propionic acid chloride and the sodium salt of methylacetoacetate, and is then heated with sodium chloride and DMSO to yield 5-[4-(6,7-dichloro-2-quinoxalinyloxy)phenoxy]-2,4-hexanedione (XV; X' is chloro and X" is chloro).

Sources & evidence

ORD record
ord-71a1b6197d1e4dcbad5f2fdbfe2f6879
Source dataset
uspto-grants-1985_06
Patent number
US04522647

Reaction notes

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