Phenylacetic Acid → Phenylacetyl chloride

HRID 1248884Notes

Reaction equation

HRID 1248884 reaction equation
S(Cl)([Cl:3])=O.[C:5]1([CH2:11][C:12]([OH:14])=O)[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1>>[C:5]1([CH2:11][C:12]([Cl:3])=[O:14])[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1

Participants

3

Reactant 2

HCID 999Phenylacetic AcidHCID 24386Thionyl Chloride

Product 1

HCID 7679Phenylacetyl chloride

Procedure

An amount described in Table 1 of thionyl chloride was added to an amount described in Table 1 of a derivative of phenylacetic acid and heated under reflux for one to four hours. Excess of thionyl chloride was distilled out under reduced pressure to obtain a derivative of phenylacetyl chloride.

Workup

  1. additionwas added to an amount
  2. temperatureheated
  3. temperatureunder reflux for one to four hours
  4. distillationExcess of thionyl chloride was distilled out under reduced pressure

Sources & evidence

ORD record
ord-d7829189892e4a60b11533813d67bf11
Source dataset
uspto-grants-1986_12
Patent number
US04627874

Reaction notes

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