Cysteamine → L-Phenylalanine

HRID 1249345Notes

Reaction equation

HRID 1249345 reaction equation
BrC(CC1NC=NC=1)C(O)=O.SC[CH:14]([NH2:22])[CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1.[C:23](=[O:26])([O-])[O-:24].[Na+].[Na+].SCCN>>[NH2:22][C@H:14]([C:23]([OH:24])=[O:26])[CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

5

Reactant 4

HCID 6058CysteamineHCID 10340Sodium CarbonateHCID 99855DL-ALPHA-BROMO-BETA-(5-IMIDAZOLYL)PROPIONIC ACIDHCID 15159715HCID 15159715, compound

Product 1

HCID 6140L-Phenylalanine

Procedure

This product is prepared from α-bromo-β-(5-imidazolyl) propionic acid and 2-mercapto-1-benzyl-ethylamine by reaction in the presence of sodium carbonate utilizing the procedure described for the analogous reaction involving 2-mercaptoethylamine as described in Example 1.

Workup

  1. customdescribed for the analogous reaction

Sources & evidence

ORD record
ord-230119d0b3ae4387b61df3cb8a66e95e
Source dataset
uspto-grants-1986_12
Patent number
US04631270

Reaction notes

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