反应详情

A solution of sodium ethoxide (0.27 g) in 3 ml of anhydrous ethanol is added with 0.657 g of ethyl (4′-phenoxyphenyl)acetate dissolved in 5 ml of ethanol, then with urea (0.18 g). The reaction mixture is refluxed for 2 hours 30 minutes, then it is cooled to room temperature and the suspended solid is filtered. The solid is redissolved in 8 ml of water and the solution is acidified with 1 N hydrochloric acid. The solid which separates is recovered by filtration to give 0.165 g of the product. m.p.>240° C.

1. temperatureThe reaction mixture is refluxed for 2 hours 30 minutes
2. filtrationthe suspended solid is filtered
3. dissolutionThe solid is redissolved in 8 ml of water
4. filtrationThe solid which separates is recovered by filtration