Hydrochloric Acid → 5-[2-(2-Chloro-4-methoxy-phenyl)-1-hydroxy-1-trifluoromethyl-propyl]-1H-pyridin-2-one
Reaction equation
[CH3:27][CH2:28][O:29][C:30]([CH3:31])=[O:32].[Cl:1][c:2]1[c:3]([CH:10]([C:11]([C:12]([F:13])([F:14])[F:15])([OH:16])[c:17]2[cH:18][n:19][c:20]([O:23][CH3:24])[cH:21][cH:22]2)[CH3:25])[cH:4][cH:5][c:6]([O:8][CH3:9])[cH:7]1.[ClH:26].[O:34]1[CH2:35][CH2:36][O:37][CH2:38][CH2:39]1.[OH2:33]>>[Cl:1][c:2]1[c:3]([CH:10]([C:11]([C:12]([F:13])([F:14])[F:15])([OH:16])[c:17]2[cH:18][nH:19][c:20](=[O:23])[cH:21][cH:22]2)[CH3:25])[cH:4][cH:5][c:6]([O:8][CH3:9])[cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-e06929fa04a2417ea72eba9af13c2d21
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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