Water → 8-Methoxycarbonyl-7-(2-methoxyphenyl)-3,3-dimethyl-3,4-dihydro-1H-quinoxalin-2-one

HRID 125100Notes

Reaction equation

HRID 125100 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:10]([c:11]1[C:12](=[O:13])[O:14][CH3:15])[NH:9][C:8](=[O:16])[C:7]([CH3:17])([CH3:18])[NH:6]2.[CH3:19][O:20][c:21]1[c:22]([B:27]([OH:28])[OH:29])[cH:23][cH:24][cH:25][cH:26]1.[CH3:30][N:31]([CH3:32])[CH:33]=[O:34].[CH3:35][CH2:36][O:37][C:38](=[O:39])[CH3:40].[OH2:41]>>[c:2]1(-[c:22]2[c:21]([O:20][CH3:19])[cH:26][cH:25][cH:24][cH:23]2)[cH:3][cH:4][c:5]2[c:10]([c:11]1[C:12](=[O:13])[O:14][CH3:15])[NH:9][C:8](=[O:16])[C:7]([CH3:17])([CH3:18])[NH:6]2

Participants

6

Reactant 5

HCID 962WaterHCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 27339582-Methoxyphenylboronic acidHCID 24780709Methyl 6-bromo-2,2-dimethyl-3-oxo-1,2,3,4-tetrahydroquinoxaline-5-carboxylate

Product 1

HCID 247808448-Methoxycarbonyl-7-(2-methoxyphenyl)-3,3-dimethyl-3,4-dihydro-1H-quinoxalin-2-one

Sources & evidence

ORD record
ord-7fec129533e84bb1818093ad6237187f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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