HCID 14004003, compound → HCID 14004009, compound

HRID 1252118Notes

Reaction equation

HRID 1252118 reaction equation
[CH3:1][O:2][C:3]1[CH:17]=[CH:16][C:6]2[CH:7]=[N:8][C:9]3[CH2:10][CH2:11][C:12](=O)[NH:13][C:14]=3[C:5]=2[CH:4]=1>O1CCCC1.B>[CH3:1][O:2][C:3]1[CH:17]=[CH:16][C:6]2[CH:7]=[N:8][C:9]3[CH2:10][CH2:11][CH2:12][NH:13][C:14]=3[C:5]=2[CH:4]=1

Participants

4

Reactant 1

HCID 14004003HCID 14004003, compound

Product 1

HCID 14004009HCID 14004009, compound

Reagents, catalysts & solvents 2

HCID 6331BoraneSolventHCID 8028TetrahydrofuranSolvent

Procedure

To a slightly turbid solution of 3.88 g of 1,4-dihydro-9-methoxybenzo[c]-1,5-naphthyridin-2(3H)-one in tetrahydrofuran (800 ml), 70 ml of borane (0.98M in tetrahydrofuran) was added over approximately one minute. A precipitate formed almost immediately. The suspension was stirred overnight at ambient temperature.

Workup

  1. customA precipitate formed almost immediately

Sources & evidence

ORD record
ord-cdc5a3ec550948039d121a34fc5167e6
Source dataset
uspto-grants-1988_05
Patent number
US04742061

Reaction notes

Loading…