反应详情

N-(3-Acetylthio-2-trifluoromethylpropanoyl)-L-proline tertbutyl ester (8 g) is dissolved in a mixture of anisole (55 ml) and trifluoroacetic acid (110 ml). After one hour storage at room temperature the solvent is removed in vacuo and the residue is precipitated several times from ether-hexane to give N-(3-acetylthio-2-trifluoromethylpropanoyl)-L-proline.

1. customAfter one hour storage at room temperature the solvent is removed in vacuo
2. customthe residue is precipitated several times from ether-hexane