Hydrochloric Acid → HCID 53964241, compound

HRID 1253175Notes

Reaction equation

HRID 1253175 reaction equation
[CH2:1]([N:3]=[C:4]([NH2:17])[NH:5][C:6]1[CH:10]=[N:9][N:8]([CH2:11][CH2:12][CH2:13][CH2:14][C:15]#[N:16])[N:7]=1)[CH3:2].Cl.[C:19](=O)([O-])[O-:20].[K+].[K+]>CO.C(Cl)(Cl)Cl>[CH2:1]([N:3]=[C:4]([NH2:17])[NH:5][C:6]1[CH:10]=[N:9][N:8]([CH2:11][CH2:12][CH2:13][CH2:14][C:15](=[NH:16])[O:20][CH3:19])[N:7]=1)[CH3:2]

Participants

6

Reactant 3

HCID 313Hydrochloric AcidHCID 11430Potassium CarbonateHCID 20137145HCID 20137145, compound

Product 1

HCID 53964241HCID 53964241, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 6212ChloroformSolvent

Procedure

A solution of 5-[4-[2-ethylguanidino)-1,2,3-triazol-2-yl]valeronitrile (1.35 g.) in MeOH (5 ml.) and chloroform (20 ml.) was saturated with gaseous HCl at 0° and the solution kept at 0° for 2.5 days. Evaporation of the solvent gave an oil which was basified with cold potassium carbonate solution and then extracted with chloroform to give methyl 5-[4-(2-ethylguanidino)1,2,3-triazol-2-yl]valerimidate (1.57 g.) which was used without further purification.

Workup

  1. customEvaporation of the solvent
  2. customgave an oil which
  3. extractionextracted with chloroform

Sources & evidence

ORD record
ord-0b2b629f402f4240a86ff970649575df
Source dataset
uspto-grants-1988_05
Patent number
US04748165

Reaction notes

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