(2-Aminobenzo[d]thiazol-6-yl)methanol → 2-Aminobenzo[d]thiazole-6-carbaldehyde

HRID 1253198Notes

Reaction equation

HRID 1253198 reaction equation
[NH2:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([CH2:11][OH:12])[CH:8]=[CH:7][C:5]=2[N:6]=1>C1COCC1.[O-2].[Mn+4].[O-2]>[NH2:1][C:2]1[S:3][C:4]2[CH:10]=[C:9]([CH:11]=[O:12])[CH:8]=[CH:7][C:5]=2[N:6]=1

Participants

4

Reactant 1

HCID 13821540(2-Aminobenzo[d]thiazol-6-yl)methanol

Product 1

HCID 138215412-Aminobenzo[d]thiazole-6-carbaldehyde

Reagents, catalysts & solvents 2

HCID 178418406HCID 178418406, compoundCatalystHCID 8028TetrahydrofuranSolvent

Procedure

110.5 g (0.613 mol) of 1a are stirred in 200 ml of THF with 319.8 g (3.678 mol) of manganese (IV) oxide at room temperature for 3 days. The reaction mixture is filtered, the residue on the filter is washed with THF, and the filtrate is evaporated in vacuo.

Workup

  1. filtrationThe reaction mixture is filtered
  2. washthe residue on the filter is washed with THF
  3. customthe filtrate is evaporated in vacuo

Sources & evidence

ORD record
ord-ca3210786c364083880abbc75021adba
Source dataset
uspto-grants-1988_05
Patent number
US04748163

Reaction notes

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