Bicarbonate Ion → tert-Butyl 4-((3-bromo-5-(trifluoromethyl)benzyloxy)methyl)-4-(pyridin-3-yl)piperidine-1-carboxylate
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH2:12][Br:13])[cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1.[C:53](=[O:54])([OH:55])[O-:56].[CH3:35][C:36]([CH3:37])([O-:38])[CH3:39].[F:41][C:42]([F:43])([F:44])[C:45]([OH:46])=[O:47].[Na+:40].[Na+:57].[O:48]1[CH2:49][CH2:50][CH2:51][CH2:52]1.[OH:14][CH2:15][C:16]1([c:29]2[cH:30][n:31][cH:32][cH:33][cH:34]2)[CH2:17][CH2:18][N:19]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:20][CH2:21]1>>[Br:1][c:2]1[cH:3][c:4]([CH2:12][O:14][CH2:15][C:16]2([c:29]3[cH:30][n:31][cH:32][cH:33][cH:34]3)[CH2:17][CH2:18][N:19]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:20][CH2:21]2)[cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-01ecc286150c4eab94eeda33a75362f1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…