Hydrogen Bromide → 7-Chloro-3-[1-(6,7-dimethoxy-4-quinazolinyl)-4-piperidinyl]-1-ethyl-1,2,3,4-tetrahydro-6-nitro-2,4-dioxoquinazoline
Reaction equation
[BrH:30].[CH3:70][CH2:71][N:72]([CH2:73][CH3:74])[CH2:75][CH3:76].[CH3:77][OH:78].[Cl:1][c:2]1[c:3]([N+:27](=[O:28])[O-:29])[cH:4][c:5]2[c:6](=[O:26])[n:7]([CH:15]3[CH2:16][CH2:17][N:18]([C:21](=[O:22])[O:23][CH2:24][CH3:25])[CH2:19][CH2:20]3)[c:8](=[O:14])[n:9]([CH2:12][CH3:13])[c:10]2[cH:11]1.[Cl:31][c:32]1[c:33]([N+:52](=[O:53])[O-:54])[cH:34][c:35]2[c:36](=[O:51])[n:37]([CH:45]3[CH2:46][CH2:47][NH:48][CH2:49][CH2:50]3)[c:38](=[O:44])[n:39]([CH2:42][CH3:43])[c:40]2[cH:41]1.[Cl:55][c:56]1[n:57][cH:58][n:59][c:60]2[cH:61][c:62]([O:68][CH3:69])[c:63]([O:66][CH3:67])[cH:64][c:65]12.[OH2:79]>>[Cl:1][c:2]1[c:3]([N+:27](=[O:28])[O-:29])[cH:4][c:5]2[c:6](=[O:26])[n:7]([CH:15]3[CH2:16][CH2:17][N:18]([C:21](=[O:22])[O:23][CH2:24][CH3:25])[CH2:19][CH2:20]3)[c:8](=[O:14])[n:9]([CH2:12][CH3:13])[c:10]2[cH:11]1.[Cl:31][c:32]1[c:33]([N+:52](=[O:53])[O-:54])[cH:34][c:35]2[c:36](=[O:51])[n:37]([CH:45]3[CH2:46][CH2:47][N:48]([c:56]4[n:57][cH:58][n:59][c:60]5[cH:61][c:62]([O:68][CH3:69])[c:63]([O:66][CH3:67])[cH:64][c:65]45)[CH2:49][CH2:50]3)[c:38](=[O:44])[n:39]([CH2:42][CH3:43])[c:40]2[cH:41]1Participants
9
Reactant 7
Product 2
Sources & evidence
- ORD record
- ord-42a85db17cee466c8581750fabd57f2e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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