HCID 58338482, compound → HCID 135862907, compound

HRID 1258476Notes

Reaction equation

HRID 1258476 reaction equation
[NH:1]1[C:5]2=[N:6][CH:7]=[CH:8][CH:9]=[C:4]2[C:3]([C:10]([NH:12][NH:13][C:14]([NH:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=S)=[O:11])=[CH:2]1>CO.C([O-])(=O)C.[Hg+2].C([O-])(=O)C>[C:17]1([NH:16][C:14]2[O:11][C:10]([C:3]3[C:4]4[C:5](=[N:6][CH:7]=[CH:8][CH:9]=4)[NH:1][CH:2]=3)=[N:12][N:13]=2)[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

4

Reactant 1

HCID 58338482HCID 58338482, compound

Product 1

HCID 135862907HCID 135862907, compound

Reagents, catalysts & solvents 2

HCID 15337Mercuric acetateCatalystHCID 887MethanolSolvent

Procedure

610 mg of 1-(1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-4-phenylthiosemicarbazide and 686 mg of mercury(II) acetate in 6 ml of MeOH are stirred at 80° C. for 2 hours in a sealed screw-lid vial. 1 drop of Na2S solution is added to the cooled reaction solution, everything is filtered through kieselguhr with suction and rinsed with warm MeOH.

Workup

  1. filtrationis filtered through kieselguhr with suction
  2. washrinsed with warm MeOH

Sources & evidence

ORD record
ord-6c726e1ef03249fdb1b7de39bf5d0c9d
Source dataset
uspto-grants-2013_06
Patent number
US08466170B2

Reaction notes

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