Hydrochloric Acid → 3-(4-carboxy-2-oxo-2H-pyridin-1-ylmethyl)-7-chloro-4-oxo-1-phenyl-1,4-dihydro-quinoline-2-carboxylic acid methyl ester

HRID 125992Notes

Reaction equation

HRID 125992 reaction equation
[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6](-[c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[c:7]2[cH:8][c:9]([Cl:28])[cH:10][cH:11][c:12]2[c:13](=[O:27])[c:14]1[CH2:15][n:16]1[c:17](=[O:26])[cH:18][c:19]([C:22](=[O:23])[O:24][CH3:25])[cH:20][cH:21]1.[ClH:37].[Na+:36].[O:38]1[CH2:39][CH2:40][CH2:41][CH2:42]1.[OH-:35]>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[n:6](-[c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[c:7]2[cH:8][c:9]([Cl:28])[cH:10][cH:11][c:12]2[c:13](=[O:27])[c:14]1[CH2:15][n:16]1[c:17](=[O:26])[cH:18][c:19]([C:22](=[O:23])[OH:24])[cH:20][cH:21]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 923Sodium ionHCID 961HydroxideHCID 8028TetrahydrofuranHCID 708168387-chloro-3-(4-methoxycarbonyl-2-oxo-2H-pyridin-1-ylmethyl)-4-oxo-1-phenyl-1,4-dihydro-quinoline-2-carboxylic acid methyl ester

Product 1

HCID 708171503-(4-carboxy-2-oxo-2H-pyridin-1-ylmethyl)-7-chloro-4-oxo-1-phenyl-1,4-dihydro-quinoline-2-carboxylic acid methyl ester

Sources & evidence

ORD record
ord-96a2d0a45f5f4bd1978cf58945dee0ca
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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