Citric Acid → N-Cbz-2,2-dimethylaziridine

HRID 126272Notes

Reaction equation

HRID 126272 reaction equation
[CH2:13]([c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1)[O:20][C:21](=[O:22])[Cl:23].[CH3:1][C:2]1([CH3:5])[NH:3][CH2:4]1.[CH3:6][CH2:7][N:8]([CH2:9][CH3:10])[CH2:11][CH3:12].[Cl:37][CH2:38][Cl:39].[OH:24][C:25]([CH2:26][C:27]([C:28](=[O:29])[OH:30])([CH2:31][C:32](=[O:33])[OH:34])[OH:35])=[O:36]>>[CH3:1][C:2]1([CH3:5])[N:3]([C:21]([O:20][CH2:13][c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)=[O:22])[CH2:4]1

Participants

6

Reactant 5

HCID 311Citric AcidHCID 6344DichloromethaneHCID 8471TriethylamineHCID 10387Benzyl chloroformateHCID 2272442,2-Dimethylaziridine

Product 1

HCID 13930700N-Cbz-2,2-dimethylaziridine

Sources & evidence

ORD record
ord-45425c7ddb9d46fb9c5176d3d3b86358
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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