反应详情

Analogously, from Z-Sar-OH and methyl N-methyl was prepared 2-[[(Benzyloxycarbonyl-methyl-amino)-acetyl]-methyl-amino]-benzoic acid methyl ester as light yellow oil (Rf 0.3 hexane:EtOAc1:2), MS: 370 (M), which was deprotected according to 6.1. and transferred into its HCl.salt by treatment with HCl/MeOH to give 2-(Methyl-methylaminoacetyl-amino)-benzoic acid methyl ester·hydrochloride, MS: 237 (MH+).