Iodine chloride → 5-Chloro-4-iodo-2-nitroaniline

HRID 1265499Notes

Reaction equation

HRID 1265499 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N+:9]([O-:11])=[O:10])=[C:6]([CH:8]=1)[NH2:7].[I:12]Cl>CC(O)=O.CC([O-])=O.[Na+]>[Cl:1][C:2]1[C:3]([I:12])=[CH:4][C:5]([N+:9]([O-:11])=[O:10])=[C:6]([NH2:7])[CH:8]=1

Participants

4

Reactant 2

HCID 24640Iodine chlorideHCID 742185-Chloro-2-nitroaniline

Product 1

HCID 223175485-Chloro-4-iodo-2-nitroaniline

Reagents, catalysts & solvents 1

HCID 23662384Sodium DiacetateSolvent

Procedure

The title compound was prepared from 5-chloro-2-nitroaniline by iodination with iodine monochloride in HOAc/NaOAc according to the general procedure A (80° C.). Obtained as an orange solid.

Workup

  1. customObtained as an orange solid

Sources & evidence

ORD record
ord-dfd014f423cb4505b930825cdb77fbac
Source dataset
uspto-grants-2003_04
Patent number
US06544985B2

Reaction notes

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