Stannous chloride dihydrate → HCID 69688527, compound

HRID 1265553Notes

Reaction equation

HRID 1265553 reaction equation
[C:1]([O:5][C:6](=[O:23])[NH:7][C:8]1[CH:13]=[C:12]([N:14]([CH:16]2[CH2:18][CH2:17]2)[CH3:15])[C:11]([Cl:19])=[CH:10][C:9]=1[N+:20]([O-])=O)([CH3:4])([CH3:3])[CH3:2].O.O.Cl[Sn]Cl>>[C:1]([O:5][C:6](=[O:23])[NH:7][C:8]1[CH:13]=[C:12]([N:14]([CH:16]2[CH2:17][CH2:18]2)[CH3:15])[C:11]([Cl:19])=[CH:10][C:9]=1[NH2:20])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 61436Stannous chloride dihydrateHCID 86586794HCID 86586794, compound

Product 1

HCID 69688527HCID 69688527, compound

Procedure

The title compound was prepared from [4-chloro-5-(cyclopropyl-methyl-amino)-2-nitro-phenyl]-carbamic acid tert.-butyl ester (Example C9) (3.2 g, 9.36 mmol) by reduction with SnCl2.2H2O according to the general procedure J (method b). Obtained as brown solid (2.00 g).

Sources & evidence

ORD record
ord-be81bfd4ade34cb4b430dfe45d13660b
Source dataset
uspto-grants-2003_04
Patent number
US06544985B2

Reaction notes

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