Acetone → HCID 86584303, compound

HRID 1265966Notes

Reaction equation

HRID 1265966 reaction equation
[S:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1.[Br:6][CH2:7][C:8](=O)[C:9]([CH3:12])([CH3:11])[CH3:10].CC(C)=[O:16]>>[Br-:6].[CH3:10][C:9]1([CH3:12])[CH2:8][CH2:7][S+:1]([CH2:2][C:3](=[O:16])[CH2:4][CH3:5])[CH2:11]1

Participants

4

Reactant 3

HCID 180AcetoneHCID 1127TetrahydrothiopheneHCID 21642Bromopinacolone

Product 1

HCID 86584303HCID 86584303, compound

Procedure

Into a four-necked flask, were charged 70.17 parts of tetrahydrothiophene and 750 parts of acetone, to which 150 parts of 1-bromopinacolone was added dropwise, followed by stirring at room temperature for 24 hours. The precipitated crystal was collected by filtration, and washed with 100 parts of tert-butylmethyl ether, and dried to obtain 161.3 parts of 3,3-dimethyl-2-oxobutyl thiacyclopentanium bromide.

Workup

  1. filtrationThe precipitated crystal was collected by filtration
  2. washwashed with 100 parts of tert-butylmethyl ether
  3. customdried

Sources & evidence

ORD record
ord-de6c3e6dc09645068285dcd80758bd49
Source dataset
uspto-grants-2003_04
Patent number
US06548220B2

Reaction notes

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