Phenylacetaldehyde → HCID 18549631, compound

HRID 1266187Notes

Reaction equation

HRID 1266187 reaction equation
[C:1]1([CH2:7][CH:8]=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:10]1[C:15](=[O:16])[O:14][CH2:13][C:11]1=O.[CH2:17]1[O:26][C:25]2[CH:24]=[CH:23][C:21]([NH2:22])=[CH:20][C:19]=2[O:18]1>C(O)C>[CH2:7]([CH:8]1[C:23]2[CH:24]=[C:25]3[O:26][CH2:17][O:18][C:19]3=[CH:20][C:21]=2[NH:22][C:11]2[CH2:13][O:14][C:15](=[O:16])[C:10]1=2)[C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 998PhenylacetaldehydeHCID 843101,3-Benzodioxol-5-amineHCID 521261Tetronic acid

Product 1

HCID 18549631HCID 18549631, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

10 mmol of phenylacetaldehyde and 10 mmol of tetronic acid are added to 10 mmol of 3,4-methylenedioxyaniline dissolved in ethanol, then the reaction mixture is heated at reflux for the night. After returning to ambient temperature, the precipitate obtained is filtered and then washed with ethanol to yield the expected product.

Workup

  1. temperaturethe reaction mixture is heated
  2. temperatureat reflux for the night
  3. customAfter returning to ambient temperature
  4. customthe precipitate obtained
  5. filtrationis filtered
  6. washwashed with ethanol

Sources & evidence

ORD record
ord-41ac18f1fb4141eabd4549bc86015f8c
Source dataset
uspto-grants-2003_04
Patent number
US06548515B1

Reaction notes

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