M-Xylene → HCID 583728, compound

HRID 1266674Notes

Reaction equation

HRID 1266674 reaction equation
[Cl-].[Al+3].[Cl-].[Cl-].[C:5]1([CH3:12])[CH:10]=[CH:9][CH:8]=[C:7]([CH3:11])[CH:6]=1.[C:13](Cl)(=[O:17])[CH:14]([CH3:16])[CH3:15]>ClCCl>[CH3:15][CH:14]([CH3:16])[C:13]([C:10]1[CH:9]=[CH:8][C:7]([CH3:11])=[CH:6][C:5]=1[CH3:12])=[O:17]

Participants

5

Reactant 3

HCID 7929M-XyleneHCID 62325Isobutyryl chlorideHCID 6451240Aluminum(III) Chloride

Product 1

HCID 583728HCID 583728, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Conditions

Temperature
0 °C

Procedure

Aluminium chloride (28.0 g, 0.21 mole) was suspended in 200 ml of anhydrous dichloromethane and cooled to 0° C. A solution of m-xylene (21.2 g, 0.2 mole) and isobutyryl chloride (21.3 g, 0.20 mole) in 50 ml of anhydrous dichloromethane was slowly added to this suspension. After the addition was completed, the reaction mixture was stirred at 0° C. for 1 h.

Workup

  1. additionAfter the addition

Sources & evidence

ORD record
ord-ddca7330a19648a8b4435264c1ec2752
Source dataset
uspto-grants-2003_04
Patent number
US06548710B2

Reaction notes

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