反应详情

A mixture of 2,4′-dibromoacetophenone (22.4 g) and 2-amino-4-picoline (8.68 g) in ethanol (80 mL) was heated at reflux temperature for 3 hours. The reaction mixture was cooled to ambient temperature and the crystalline solid-isolated by filtration, washed with ethanol and dried in vacuo to give the title compound (13.1 g).

1. temperaturewas heated
2. temperatureat reflux temperature for 3 hours
3. customthe crystalline solid-isolated by filtration
4. washwashed with ethanol
5. customdried in vacuo