3-Nitrobenzonitrile → 3-Nitrobenzamidinium hydrochloride

HRID 1270295Notes

Reaction equation

[Cl-:1].[NH4+:2].C[Al](C)C.[N+:7]([C:10]1[CH:11]=[C:12]([CH:15]=[CH:16][CH:17]=1)[C:13]#[N:14])([O-:9])=[O:8]>>[ClH:1].[N+:7]([C:10]1[CH:11]=[C:12]([C:13](=[NH:2])[NH2:14])[CH:15]=[CH:16][CH:17]=1)([O-:9])=[O:8]

Participants

Reactant 3

HCID 120793-Nitrobenzonitrile

HCID 25517Ammonium Chloride

HCID 16682925Trimethylaluminum

Product 1

HCID 124561623-Nitrobenzamidinium hydrochloride

Procedure

7.22 g (135 mmol) of ammonium chloride are reacted analogously to example 1A with 135 mmol of trimethylaluminum (67.5 ml of 2 M solution in hexane) and 10 g (67.51 mmol) of 3-nitrobenzonitrile.

Sources & evidence

ORD record: ord-dd5993f666a54fdfbe29e4972de0a74c
Source dataset: uspto-grants-2007_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07202243B2

Reaction notes

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