反应详情

5-(6-Fluoro-pyridin-2-yl)-2,4-dimethoxy-pyrimidine (Prep74, 230 mg, 0.98 mmol) was dissolved in a solution of 4N HCl in dioxane (4 ml). After refluxing the reaction mixture for 1 hour, the solvent was removed under vacuum to give 200 mg of the title compound (84% yield)

1. temperatureAfter refluxing the reaction mixture for 1 hour
2. customthe solvent was removed under vacuum