1H-1,2,4-Triazole → 1H-1,2,4-Triazole, 1-phenyl-

HRID 1270698Notes

Reaction equation

HRID 1270698 reaction equation
I[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH:8]1[CH:12]=[N:11][CH:10]=[N:9]1.C(=O)([O-])[O-].[Cs+].[Cs+]>CN(C=O)C>[C:2]1([N:8]2[CH:12]=[N:11][CH:10]=[N:9]2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 92571H-1,2,4-TriazoleHCID 10796Cesium carbonateHCID 11575Iodobenzene

Product 1

HCID 834321H-1,2,4-Triazole, 1-phenyl-

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Operating protocol A (82° C., 24 hours) was followed using 117 mg of Chxn-Py-Al (0.4 mmoles), 336 μl of iodobenzene (3 mmoles), 138 mg of 1,2,4-triazole (2 mmoles), 1.042 g of caesium carbonate (3.2 mmoles) and 1.2 ml of DMF.

Workup

  1. customA (82° C., 24 hours)

Sources & evidence

ORD record
ord-d21407fde4664c9ba4e5cb89aeae7b46
Source dataset
uspto-grants-2007_04
Patent number
US07202367B2

Reaction notes

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