3,5-Dimethylphenol → HCID 10397868, compound

HRID 1270707Notes

Reaction equation

HRID 1270707 reaction equation
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][N:3]=1.[CH3:8][C:9]1[CH:10]=[C:11]([OH:16])[CH:12]=[C:13]([CH3:15])[CH:14]=1>CN(C=O)C>[N:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[O:16][C:11]1[CH:12]=[C:13]([CH3:15])[CH:14]=[C:9]([CH3:8])[CH:10]=1

Participants

4

Reactant 2

HCID 79483,5-DimethylphenolHCID 79732-Bromopyridine

Product 1

HCID 10397868HCID 10397868, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

General procedure A (110° C., 24 hours) was followed using 117 mg of Chxn-Py-Al (0.4 mmoles), 292 μl of 2-bromopyridine (3 mmoles), 244 mg of 3,5-dimethylphenol (2 mmoles), 600 mg of ground and activated 3 Å molecular sieve and 1.2 ml of DMF.

Workup

  1. customGeneral procedure A (110° C., 24 hours)

Sources & evidence

ORD record
ord-3e33e4ff67d84e9e846ee28bb1a5ec80
Source dataset
uspto-grants-2007_04
Patent number
US07202367B2

Reaction notes

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