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HRID1270816

反应详情

EQUATION

反应方程式

HRID 1270816 的结构方程式

REACTANTS

反应物

3
结构：O=P(Cl)(Cl)Cl
HCID24813

Phosphoric trichloride

Cl3OP

结构：CC(C)(C)OC(=O)N1Cc2ccccc2CC1C(=O)NCC(=O)c1ccccc1
HCID23570725

未命名化合物

结构：O=C(CNC(=O)C1Cc2ccccc2CN1C(=O)OCc1ccccc1)c1ccccc1
HCID66892649

未命名化合物

PRODUCTS

生成物

1
结构：c1ccc(-c2cnc(C3Cc4ccccc4CN3)o2)cc1
HCID22147680

未命名化合物

PROCEDURE

实验过程

Dehydration of 3-(2-oxo-2-phenyl-ethylcarbamoyl)-3,4-dihydro-1H-isoquinoline-2-carboxylic acid benzyl ester (prepared in a similar manner as 3-(2-oxo-2-phenyl-ethylcarbamoyl)-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert butyl ester of Example 1) with POCl3 yields the following intermediate compound:

WORKUP

后处理

  1. customyields the following intermediate compound