反应详情

To a solution of 4.86 g of 5-hydroxy-1-tetralone in 50 ml of acetonitrile, 5.13 g of benzyl bromide and 6.22 g of potassium carbonate were added and the mixture was heated at reflux for 4 hours. The insoluble matter was removed by filtration and the filtrate was concentrated. The residue was purified by silica gel column chromatography to obtain 6.62 g of the desired compound as a pale yellow oily substance.

1. temperaturethe mixture was heated
2. temperatureat reflux for 4 hours
3. customThe insoluble matter was removed by filtration
4. concentrationthe filtrate was concentrated
5. customThe residue was purified by silica gel column chromatography