N-[2,4-bis(phenylmethoxy)phenyl]-2,2,2-trifluoroacetamide → N-(2,4-dihydroxyphenyl)-2,2,2-trifluoro-acetamide

HRID 1271823Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1271823
C1(C[O:8][C:9]2[CH:14]=[C:13]([O:15]CC3C=CC=CC=3)[CH:12]=[CH:11][C:10]=2[NH:23][C:24](=[O:29])[C:25]([F:28])([F:27])[F:26])C=CC=CC=1.[H][H]>[Pd].C(O)C>[OH:8][C:9]1[CH:14]=[C:13]([OH:15])[CH:12]=[CH:11][C:10]=1[NH:23][C:24](=[O:29])[C:25]([F:26])([F:27])[F:28]

Komponenten

5

Edukt 2

HCID 18454995N-[2,4-bis(phenylmethoxy)phenyl]-2,2,2-trifluoroacetamideHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 18454996N-(2,4-dihydroxyphenyl)-2,2,2-trifluoro-acetamide

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

A mixture of 1.5 grams (0.0036 mole) of, N-[2,4-bis(phenylmethoxy)phenyl]-2,2,2-trifluoroacetamide and 0.2 gram (catalyst) of 10% palladium on carbon in 125 mL of ethanol was treated with hydrogen gas in a Parr Hydrogenator, yielding 0.80 gram of the subject compound. The NMR spectrum was consistent with the proposed structure.

Quellen und Nachweise

ORD-Eintrag
ord-5f443e488cd747bfbbdd4750efefd45d
Quelldatensatz
uspto-grants-2007_04
Patentnummer
US07208450B2

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