反应详情

According to the procedure indicated in Example 1, reaction of 4-mercaptopyridine with 2-chloromethyl-4-(2-furylmethylthio)-3-methylpyridine hydrochloride and sodium hydroxide solution, subsequent chromatography on silica gel (ethyl acetate/ethanol) and crystallization from diisopropyl ether gives the title compound as a colorless powder; m.p. 126-128° C.; yield 89% of theory.