反应详情

According to the procedure indicated in Example 7, reaction of 4-(3-chloropropylthio)-3-methyl-2-[(4-pyridinylthio)methyl]pyridine with imidazole (2.0 equivalents) and potassium carbonate and subsequent chromatography on silica gel (dichloromethane/acetone/NH3 aq) gives, after crystallization from diisopropyl ether, the title compound; m.p. 117-119° C.; yield 32% of theory.

1. customgives
2. customafter crystallization from diisopropyl ether