HCID 15887602, compound → HCID 22117680, compound

HRID 1275686Notes

Reaction equation

HRID 1275686 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([CH:23]=[CH:24][CH:25]=1)[CH2:7][O:8][C:9]1[CH:22]=[CH:21][C:12]([O:13][C:14]2[CH:20]=[CH:19][CH:18]=[CH:17][C:15]=2[NH2:16])=[CH:11][CH:10]=1)([O-:3])=[O:2].C(OCC)(=O)C.[ClH:32]>C(OCC)(=O)C>[ClH:32].[N+:1]([C:4]1[CH:5]=[C:6]([CH:23]=[CH:24][CH:25]=1)[CH2:7][O:8][C:9]1[CH:22]=[CH:21][C:12]([O:13][C:14]2[CH:20]=[CH:19][CH:18]=[CH:17][C:15]=2[NH2:16])=[CH:11][CH:10]=1)([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 15887602HCID 15887602, compoundHCID 21866389Hydrogen chloride-ethyl acetate

Product 1

HCID 22117680HCID 22117680, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

2-[4-(3-Nitrobenzyloxy)phenoxy]aniline (0.64 g, 1.9 mmol) was dissolved in ethyl acetate (10 ml), and 4 N hydrogen chloride-ethyl acetate solution (1 ml) was added, followed by stirring for 30 minutes. The solvent was evaporated under reduced pressure, and the residue was crystallized from diethyl ether to give the title compound (0.55 g).

Workup

  1. customThe solvent was evaporated under reduced pressure
  2. customthe residue was crystallized from diethyl ether

Sources & evidence

ORD record
ord-b3a0cc36d58846c1bff4a7149f384fe6
Source dataset
uspto-grants-2000_12
Patent number
US06162832

Reaction notes

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