Hydrochloric Acid → HCID 12698924, compound

HRID 1277434Notes

Reaction equation

HRID 1277434 reaction equation
[ClH:1].[CH3:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]=[C:8]([C:13]([CH2:15][N:16]1[CH:20]=[CH:19][N:18]=[CH:17]1)=[O:14])[CH:7]=[CH:6]2>>[ClH:1].[CH3:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]=[C:8]([C:13]([CH2:15][N:16]1[CH:20]=[CH:19][N:18]=[CH:17]1)=[O:14])[CH:7]=[CH:6]2

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 12698923HCID 12698923, compound

Product 1

HCID 12698924HCID 12698924, compound

Procedure

Ethereal hydrogen chloride is added dropwise to a solution of 1.0 g. 1-[(6-methyl-2-naphthoyl)methyl]imidazole in 100 ml. ether until precipitation is complete. The product is filtered, washed with ether, airdried and recrystallized from methanol/acetone to yield 1-[(6-methyl-2-naphthoyl)methyl]imidazole hydrochloride, m.p. 271°-272° C. (decomp).

Workup

  1. customether until precipitation
  2. filtrationThe product is filtered
  3. washwashed with ether
  4. customrecrystallized from methanol/acetone

Sources & evidence

ORD record
ord-b14e71c63a2247f494df5449edc922fa
Source dataset
uspto-grants-1981_07
Patent number
US04277486

Reaction notes

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