Formic Acid → HCID 23453303, compound

HRID 1277718Notes

Reaction equation

HRID 1277718 reaction equation
[NH:1]([C:3]1[CH:8]=[CH:7][C:6]([CH2:9][C:10]([OH:12])=[O:11])=[CH:5][CH:4]=1)[NH2:2].[CH:13]([O-])=[O:14].[Na+].C(OCC)=O.C(O)=O>C(O)C>[CH:13]([NH:2][NH:1][C:3]1[CH:4]=[CH:5][C:6]([CH2:9][C:10]([OH:12])=[O:11])=[CH:7][CH:8]=1)=[O:14]

Participants

6

Reactant 4

HCID 284Formic AcidHCID 8025Ethyl formateHCID 419175(4-Hydrazinylphenyl)acetic acidHCID 2723810Sodium Formate

Product 1

HCID 23453303HCID 23453303, compoundYield 56.7%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

p-Hydrazinophenylacetic acid (3.32 g, 0.02 M), sodium formate (2.72 g, 0.04 m), ethyl formate (49 g), formic acid (10 ml) was refluxed for one hour in ethanol (100 ml). The residue was removed by filtration and the filtrate on concentration afforded light-yellow crystals (2.2 g, 55 percent).

Workup

  1. customThe residue was removed by filtration
  2. concentrationthe filtrate on concentration

Sources & evidence

ORD record
ord-4aa814b6d5ce40d1bd3654ab3b64cc89
Source dataset
uspto-grants-1981_07
Patent number
US04278748

Reaction notes

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