Ammonium Hydroxide → 2-Iodobenzamide

HRID 1277906Notes

Reaction equation

HRID 1277906 reaction equation
[OH-].[NH4+:2].[I:3][C:4]1[CH:12]=[CH:11][CH:10]=[CH:9][C:5]=1[C:6](Cl)=[O:7]>>[I:3][C:4]1[CH:12]=[CH:11][CH:10]=[CH:9][C:5]=1[C:6]([NH2:2])=[O:7]

Participants

3

Reactant 2

HCID 14923Ammonium HydroxideHCID 691122-Iodobenzoyl chloride

Product 1

HCID 775292-Iodobenzamide

Procedure

A total of 50 ml of a 15 M ammonium hydroxide solution was reacted with 15 g o-iodobenzoyl chloride for 20 minutes. The crude product was recovered as in Example 1. The product was recrystallized from ethanol to yield 7.8 g of o-iodobenzamide, m.p. 187°-189°, Rf 0.63.

Workup

  1. customThe crude product was recovered as in Example 1
  2. customThe product was recrystallized from ethanol

Sources & evidence

ORD record
ord-73879bd1802840bea979c0bba468c15c
Source dataset
uspto-grants-1981_07
Patent number
US04279887

Reaction notes

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