Sodium Chloride → HCID 962071, compound

HRID 1277911Notes

Reaction equation

HRID 1277911 reaction equation
[NH:1]1[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[I:7][C:8]1[CH:16]=[CH:15][CH:14]=[CH:13][C:9]=1[C:10](Cl)=[O:11].[Na+].[Cl-].C1C=CC=CC=1.CCCCCC>O1CCCC1>[I:7][C:8]1[CH:16]=[CH:15][CH:14]=[CH:13][C:9]=1[C:10]([N:1]1[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1)=[O:11]

Participants

6

Reactant 4

HCID 5234Sodium ChlorideHCID 8083MorpholineHCID 691122-Iodobenzoyl chlorideHCID 110624Benzene hexane

Product 1

HCID 962071HCID 962071, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent2×

Procedure

A solution of 15 ml of morpholine in 30 ml of tetrahydrofuran was reacted with a solution of 8.0 g o-iodobenzoyl chloride in 20 ml tetrahydrofuran for 10 minutes. The product was obtained in the manner described in Example 3, using saturated NaCl instead of H2O. There was obtained by recrystallization from benzene/hexane 6.8 g of N-o-iodobenzoylmorpholine as hard, translucent crystals, m.p. 86°-87°, Rf 0.73.

Workup

  1. customThe product was obtained in the manner

Sources & evidence

ORD record
ord-ed8e331728674dffb2c70b8c5d699332
Source dataset
uspto-grants-1981_07
Patent number
US04279887

Reaction notes

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