反应详情

A mixture of 19 g. diethyl malate and 0.1 g. of 36% hydrochloric acid was added to a 50 ml. round-bottom flask equipped with an addition funnel, static nitrogen head, condensor, heating mantle, thermometer, and magnetic stirrer. Ethyl vinyl ether was then added, dropwise, at 41° to 43° C. over a one-hour period and quenched with 0.4 g. of solid sodium carbonate. Distillation was performed directly on the mixture (short path column):

1. additionA mixture of 19 g
2. customround-bottom flask equipped with an addition funnel
3. temperaturestatic nitrogen head, condensor, heating mantle
4. waitdropwise, at 41° to 43° C. over a one-hour period
5. customquenched with 0.4 g
6. distillationDistillation