Hydrogen Peroxide → HCID 70527488, compound

HRID 1278224Notes

Reaction equation

HRID 1278224 reaction equation
[Br:1][C:2]1[CH:3]=[N:4][N:5]2[C:10]([C:11]3[CH:12]=[N:13][CH:14]=[CH:15][CH:16]=3)=[CH:9][CH:8]=[N:7][C:6]=12.[OH:17]O>C(O)(=O)C>[N+:13]1([O-:17])[CH:14]=[CH:15][CH:16]=[CH:11][CH:12]=1.[Br:1][C:2]1[CH:3]=[N:4][N:5]2[C:10]([C:11]3[CH:12]=[N:13][CH:14]=[CH:15][CH:16]=3)=[CH:9][CH:8]=[N:7][C:6]=12

Participants

4

Reactant 2

HCID 784Hydrogen PeroxideHCID 12766251HCID 12766251, compound

Product 1

HCID 70527488HCID 70527488, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A mixture of 0.90 g. of 3-bromo-7-(3-pyridyl)pyrazolo[1,5-a]pyrimidine, 25 ml. of glacial acetic acid and 5 ml. of 30% hydrogen peroxide is heated on a steam bath for 4 hours. The mixture is filtered and the solid recrystallized from ethanol to give 0.40 g. of the product of the example, m.p. 280°-284° C.

Workup

  1. additionA mixture of 0.90 g
  2. filtrationThe mixture is filtered
  3. customthe solid recrystallized from ethanol
  4. customto give 0.40 g

Sources & evidence

ORD record
ord-e40823577067435fa05d5cdcb232094f
Source dataset
uspto-grants-1981_07
Patent number
US04281000

Reaction notes

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