CHEBI:5834 → HCID 70148574, compound

HRID 1278549Notes

Reaction equation

HRID 1278549 reaction equation
[Na:1].[CH3:2][CH:3]([C:5]([C@@:7]12[C@@:17]([CH2:19][CH2:20][CH:21]=[C:22]([CH3:24])[CH3:23])([CH3:18])[C@@H:16]([CH2:25][CH:26]=[C:27]([CH3:29])[CH3:28])[CH2:15][C@@:12]([CH2:30][CH:31]=[C:32]([CH3:34])[CH3:33])([C:13]1=[O:14])[C:11]([OH:35])=[C:10]([CH2:36][CH:37]=[C:38]([CH3:40])[CH3:39])[C:8]2=[O:9])=[O:6])[CH3:4]>CO>[CH3:4][CH:3]([C:5]([C@@:7]12[C@@:17]([CH2:19][CH2:20][CH:21]=[C:22]([CH3:23])[CH3:24])([CH3:18])[C@@H:16]([CH2:25][CH:26]=[C:27]([CH3:28])[CH3:29])[CH2:15][C@@:12]([CH2:30][CH:31]=[C:32]([CH3:34])[CH3:33])([C:13]1=[O:14])[C:11]([OH:35])=[C:10]([CH2:36][CH:37]=[C:38]([CH3:40])[CH3:39])[C:8]2=[O:9])=[O:6])[CH3:2].[Na:1]

Participants

4

Reactant 2

HCID 441298CHEBI:5834HCID 5360545Sodium

Product 1

HCID 70148574HCID 70148574, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

23 mg (1 mmol) sodium is dissolved in 50 ml anhydrous methanol. 536 mg (1 mmol) hyperforin is dissolved in this solution under stirring, and the solution evaporated. The residue is dissolved in 100 ml water and lyophilised. Yield: 556 mg of a light-coloured powder (99.6% of theoretical). Mp.: Degradation from 170° C. IR: 1420-1500 cm−(sv).

Workup

  1. customthe solution evaporated
  2. dissolutionThe residue is dissolved in 100 ml water
  3. customfrom 170° C

Sources & evidence

ORD record
ord-de10881907ed4ef0a57acda5aa179634
Source dataset
uspto-grants-2002_09
Patent number
US06444662B1

Reaction notes

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