Hydrochloric Acid → HCID 22476022, compound

HRID 1278922Notes

Reaction equation

HRID 1278922 reaction equation
C1(=O)N[C:4](=[O:6])[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12.NN.Cl.N[CH2:16][C:17]1[CH:18]=[N:19]C(C#N)=N[CH:22]=1.Cl>>[NH2:19][CH2:18][C:17]1[CH:16]=[CH:22][C:17]([C:18]#[N:19])=[CH:16][C:22]=1[O:6][CH2:4][C:3]1[CH:2]=[CH:10][CH:9]=[CH:8][CH:7]=1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 6809PhthalimideHCID 9321HydrazineHCID 22476050182287-56-5

Product 1

HCID 22476022HCID 22476022, compound

Procedure

Synthesis took place via the stage of the corresponding phthalimide as in Example 3.(f). The hydrazine cleavage was carried out as in Example 3.(g). The free amine was generated at pH 9-10 from the initially produced hydrochloride and was extracted from the aqueous solution with ether. 1H-NMR (DMSO-d6, δ in ppm): 7.65-7.25 (8H), 5.20 (s, 2H), 3.80 (s, 2H), ca. 3.0 (broad signal, NH2)

Workup

  1. customSynthesis
  2. extractionwas extracted from the aqueous solution with ether

Sources & evidence

ORD record
ord-6a86f8435a8d4b6582733b7dc58efbca
Source dataset
uspto-grants-2002_09
Patent number
US06444817B1

Reaction notes

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