Diethyl disulfide → HCID 18427287, compound

HRID 1279192Notes

Reaction equation

HRID 1279192 reaction equation
N[C:2]1[CH:3]=[N:4][C:5]([Cl:9])=[C:6]([Cl:8])[CH:7]=1.[CH2:10]([S:12]SCC)[CH3:11].N(OC(C)(C)C)=O>C(Cl)Cl>[Cl:9][C:5]1[C:6]([Cl:8])=[CH:7][C:2]([S:12][CH2:10][CH3:11])=[CH:3][N:4]=1

Participants

5

Reactant 3

HCID 8077Diethyl disulfideHCID 10906Tert-Butyl nitriteHCID 145952195-Amino-2,3-dichloropyridine

Product 1

HCID 18427287HCID 18427287, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Procedure

24.45 g (0.15 mol) of 3-amino-5,6-dichloropyridine in 280 ml of methylene chloride were reacted with 36.6 g (0.3 mol) of diethyl disulfide and 23.2 g (0.225 mol) of tert-butyl nitrite in 130 ml of methylene chloride by a method similar to Example 1, Precursor α. After working up and subsequently washing the crude product with ethanol, 13.3 g of product of value were obtained.

Workup

  1. washsubsequently washing the crude product with ethanol, 13.3 g of product of value
  2. customwere obtained

Sources & evidence

ORD record
ord-b877751b751f4ffaaf3d05e654e96f2e
Source dataset
uspto-grants-2002_09
Patent number
US06448205B1

Reaction notes

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