Ammonium Chloride → HCID 178477935, compound

HRID 127941Notes

Reaction equation

HRID 127941 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:12]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[N:11]=[CH:10][C:9]=2[CH2:19][C:20]#[N:21])=[CH:4][CH:3]=1.[N-:22]=[N+:23]=[N-:24].[Na+].[NH4+].[Cl-]>CN(C=O)C>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[N:12]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[N:11]=[CH:10][C:9]=2[CH2:19][C:20]2[NH:24][N:23]=[N:22][N:21]=2)=[CH:6][CH:7]=1

Participants

5

Reactant 3

HCID 25517Ammonium ChlorideHCID 33557Sodium AzideHCID 53675380HCID 53675380, compound

Product 1

HCID 178477935HCID 178477935, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A mixture of 29.4 g of (5-p-chlorophenyl-1-phenyl-pyrazol-4-yl)-acetonitrile, 8.06 g of sodium azide, 6.64 g of NH4Cl and 140 ml of dry DMF is heated at 120° for 17 hours, with stirring, and is then evaporated. After the customary working up, 5-p-chlorophenyl-1-phenyl-4-(tetrazol-5-ylmethyl)-pyrazole is obtained; m.p. 230°-232°.

Workup

  1. temperatureis heated at 120° for 17 hours
  2. customis then evaporated

Sources & evidence

ORD record
ord-ff26bf1ac36349808214f328ab332ac0
Source dataset
uspto-grants-1981_03
Patent number
US04258047

Reaction notes

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