反应详情

1-Phenyl-2-(3-sulfamoyl-4-chlorobenzoyl)-hydrazine 5 g (0.015 mol) was dissolved in dimethylformamide (15 ml). To this was added allyl bromide 2.8 g (0.023 mol) and the mixture was heated at 95°-100° C. for about 1.5 hours. The reaction mixture was cooled and diluted with 30 ml of isopropanol and added slowly to about 900 ml of cold water. The precipitate was collected by filtration, washed with water and dried under reduced pressure to provide 1-allyl-1-phenyl-2-(3-sulfamoyl-4-chlorobenzoyl)-hydrazine (m.p. 99°-101° C.).

1. temperaturethe mixture was heated at 95°-100° C. for about 1.5 hours
2. temperatureThe reaction mixture was cooled
3. filtrationThe precipitate was collected by filtration
4. washwashed with water
5. customdried under reduced pressure