Benzyl Bromide → N-Benzyl-2-hydroxy-N,N-bis(2-hydroxyethyl)ethan-1-aminium bromide

HRID 1280315Notes

Reaction equation

[N:1]([CH2:8][CH2:9][OH:10])([CH2:5][CH2:6][OH:7])[CH2:2][CH2:3][OH:4].[CH2:11]([Br:18])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[Br-:18].[CH2:11]([N+:1]([CH2:8][CH2:9][OH:10])([CH2:5][CH2:6][OH:7])[CH2:2][CH2:3][OH:4])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

Reactant 2

HCID 7498Benzyl Bromide

HCID 7618Triethanolamine

Product 1

HCID 22472341N-Benzyl-2-hydroxy-N,N-bis(2-hydroxyethyl)ethan-1-aminium bromide

Procedure

A] Benzyl tris(hydroxyethyl)ammonium bromide was synthesized from triethanolamine and benzyl bromide using the procedure of Rengan et al (J.Chem.Soc.Chem.Commun., 10, 1992, 757).

Sources & evidence

ORD record: ord-92f387a625c84031acf51f4b7e0c77cd
Source dataset: uspto-grants-2002_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06451500B1

Reaction notes

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