Potassium Bromide → HCID 22237613, compound

HRID 1281435Notes

Reaction equation

[CH2:1]([C:7]1[CH:8]=[C:9]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[C:10]([O:19][CH2:20][C:21]([O:23]C)=[O:22])=[C:11]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:12]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].[K+].[Br-]>>[CH2:1]([C:7]1[CH:12]=[C:11]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[C:10]([O:19][CH2:20][C:21]([OH:23])=[O:22])=[C:9]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[CH:8]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6]

Participants

Reactant 2

HCID 253877Potassium Bromide

HCID 86758525HCID 86758525, compound

Product 1

HCID 22237613HCID 22237613, compound

Procedure

The title compound was prepared as a white solid (0.559 g, 67%) from (5′-Hexyl-[1,1′;3′,1″]terphenyl-2′-yloxy)acetic acid, methyl ester (0.870 g, 2.161 mmol) using a procedure similar to step 4 of example 165; mp 87-89° C.; 1H NMR (400 MHz, DMSO-d6) δ 0.82-0.86 (m, 3H), 1.22-1.37 (m, 6H), 1.56-1.64 (m, 2H), 2.61 (t, J=7.5 Hz, 2H), 3.71 (s, 2H), 7.16 (s, 2H), 7.32-7.37 (m, 2H), 7.39-7.44 (m, 4H), 7.59 (m, 4H), 12.47 (broad s, 1H); IR (KBr) 3450, 2920, 1725, 1420, 1210 cm−1; mass spectrum [EI], m/z 388 M+; Anal. Calcd. for C26H28O3: C, 80.38; H, 7.26; N, 0.00, Found: C, 79.99; H, 7.24; N, 0.13.

Sources & evidence

ORD record: ord-d0408a8a46f4497891b10edfa9893b9c
Source dataset: uspto-grants-2002_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06451827B2

Reaction notes

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