反应详情

5-(2-fluoro-3-pyridinyl)-1-(4-{(1S)-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hex-3-yl}butyl)-2,4(1H,3H)-pyrimidinedione was treated with 4N HCl in dioxane (2 eq). After evaporation of the solvent and trituration with diethyl ether, 41 mg of the title compound were obtained as a white powder. (89% yield)

1. customAfter evaporation of the solvent and trituration with diethyl ether